The USS Enterprise left Norfolk Sunday on its 22nd – and final – deployment. The Navy’s first nuclear-powered flattop has been cruising the world’s oceans since her commissioning in 1961, playing a role in major U.S. military actions ranging from the Cuban missile crisis to the post-9/11 wars in Afghanistan and Iraq. It’s a safe bet that 100,000 sailors have tended to the Big E over the past half-century.